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Hee-Yeon Cho Selected Research

NEO212

1/2020Developing a clinically relevant radiosensitizer for temozolomide-resistant gliomas.
1/2020Pharmacokinetic properties of the temozolomide perillyl alcohol conjugate (NEO212) in mice.
1/2018NEO212 Inhibits Migration and Invasion of Glioma Stem Cells.
8/2015Chemotherapeutic effect of a novel temozolomide analog on nasopharyngeal carcinoma in vitro and in vivo.
3/2015A novel temozolomide analog, NEO212, with enhanced activity against MGMT-positive melanoma in vitro and in vivo.
8/2014NEO212, temozolomide conjugated to perillyl alcohol, is a novel drug for effective treatment of a broad range of temozolomide-resistant gliomas.

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Hee-Yeon Cho Research Topics

Disease

23Neoplasms (Cancer)
12/2023 - 09/2009
9Glioma (Gliomas)
01/2020 - 11/2012
8Glioblastoma (Glioblastoma Multiforme)
12/2023 - 05/2014
7Brain Neoplasms (Brain Tumor)
12/2023 - 05/2014
4Breast Neoplasms (Breast Cancer)
12/2021 - 09/2009
2Melanoma (Melanoma, Malignant)
01/2023 - 03/2015
2Neoplasm Metastasis (Metastasis)
10/2021 - 05/2014
2Multiple Myeloma
03/2019 - 01/2018
2Choroidal Neovascularization
05/2018 - 01/2017
2Human Influenza (Influenza)
01/2012 - 12/2010
2Status Epilepticus (Complex Partial Status Epilepticus)
05/2008 - 03/2007
1Lymphoma (Lymphomas)
12/2023
1Hypoxia (Hypoxemia)
05/2018
1Lung Neoplasms (Lung Cancer)
07/2017
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
07/2017
1Macular Degeneration (Age-Related Maculopathy)
01/2017
1Nasopharyngeal Carcinoma
08/2015
1Malaria
03/2015
1Heart Diseases (Heart Disease)
11/2014
1Metabolic Diseases (Metabolic Disease)
11/2014
1Turcot syndrome
08/2014

Drug/Important Bio-Agent (IBA)

13perillyl alcoholIBA
12/2023 - 11/2012
11Temozolomide (Temodar)FDA LinkGeneric
12/2023 - 11/2012
6NEO212IBA
01/2020 - 08/2014
4MethyltransferasesIBA
12/2023 - 08/2014
3Chloroquine (Aralen)FDA LinkGeneric
12/2023 - 12/2014
3Trastuzumab (Herceptin)FDA Link
12/2021 - 09/2009
3DNA (Deoxyribonucleic Acid)IBA
01/2020 - 08/2014
3Alkylating AgentsIBA
08/2015 - 05/2014
2RolipramIBA
12/2023 - 01/2018
2Proteasome InhibitorsIBA
03/2019 - 01/2018
2Bortezomib (Velcade)FDA Link
03/2019 - 01/2018
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
05/2018 - 03/2010
2Nelfinavir (Viracept)FDA Link
11/2012 - 09/2009
2Celecoxib (Celebrex)FDA Link
11/2012 - 09/2009
2VaccinesIBA
01/2012 - 12/2010
22,5-dimethylcelecoxibIBA
03/2010 - 09/2009
1Chimeric Antigen ReceptorsIBA
12/2023
1bafilomycin A1IBA
12/2023
1Sirolimus (Rapamycin)FDA Link
12/2023
1Lysosomal-Associated Membrane Protein 1IBA
12/2023
1Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA
12/2023
1Phosphotransferases (Kinase)IBA
12/2023
1Transcription Factors (Transcription Factor)IBA
12/2023
1AntibodiesIBA
01/2023
1Monoclonal AntibodiesIBA
10/2021
1Ado-Trastuzumab EmtansineIBA
10/2021
1human ERBB2 proteinIBA
10/2021
1O-(6)-methylguanineIBA
01/2020
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2019
1afliberceptIBA
05/2018
1LuciferasesIBA
01/2018
1ErbB Receptors (EGF Receptor)IBA
07/2017
1CRISPR-Associated Protein 9IBA
07/2017
1Cisplatin (Platino)FDA LinkGeneric
08/2015
1Quinine (Quinson)FDA Link
03/2015
1Antimalarials (Antimalarial Agents)IBA
03/2015
1Hydroxychloroquine (Plaquenil)FDA LinkGeneric
03/2015
1Quinacrine (Mepacrine)IBA
03/2015
1quinolineIBA
03/2015
1Mefloquine (Lariam)FDA LinkGeneric
03/2015
1Protein Kinase CIBA
11/2014
1AgarIBA
11/2014
1Small Interfering RNA (siRNA)IBA
11/2014
1GuanineIBA
08/2014
1Proteins (Proteins, Gene)FDA Link
08/2014
1AmidesIBA
05/2014
1Monoterpenes (Monoterpenoids)IBA
11/2012
1O(6)-Methylguanine-DNA MethyltransferaseIBA
11/2012
1Cytotoxins (Cytolysins)IBA
11/2012
1Influenza Vaccines (Influenza Vaccine)FDA Link
12/2010
1Endothelin-1 (Endothelin 1)IBA
03/2010
1Interleukin-8 (Interleukin 8)IBA
03/2010
1Doxorubicin (Adriamycin)FDA LinkGeneric
09/2009
1HIV Protease InhibitorsIBA
09/2009
1Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
09/2009
1Drug CombinationsIBA
09/2009
1Paclitaxel (Taxol)FDA LinkGeneric
09/2009
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
09/2009
1IGF Type 1 Receptor (IGF 1 Receptor)IBA
05/2008
1Protein Tyrosine PhosphatasesIBA
03/2007
1Pilocarpine (Ocusert)FDA LinkGeneric
03/2007

Therapy/Procedure

7Therapeutics
12/2023 - 05/2014
3Drug Therapy (Chemotherapy)
08/2019 - 08/2014
2Radiotherapy
01/2020 - 12/2014
2Intranasal Administration
08/2019 - 11/2012
2Lasers (Laser)
05/2018 - 01/2017
1Catheters
03/2019